Author Correction: De novo design of quasisymmetric two-component protein cages

Researchers published an author correction for their study "De novo design of quasisymmetric two-component protein cages" on June 9, 2026, in the journal Nature. The original research, published online, detailed the creation of novel protein structures through computational design. This correction addresses specific aspects of the experimental validation or computational methodology used in the de novo design process. The study focused on engineering protein cages with precise symmetry, a significant advancement in protein engineering and synthetic biology. The ability to design such complex protein architectures from scratch has implications for drug delivery, vaccine development, and the creation of new biomaterials. The correction ensures the accuracy and reproducibility of the findings presented in the original Nature publication, reinforcing the scientific rigor of the research. The authors aimed to demonstrate a new paradigm in protein design by building complex, self-assembling protein structures with predictable geometries and functionalities. This work contributes to the growing field of artificial protein design, pushing the boundaries of what can be achieved in creating bespoke protein machinery for various applications.