Analysis of 173,303 exomes and genomes in the Pakistan Genome Resource

The Pakistan Genome Resource (PGR) published biobank data from 173,303 individuals on June 17, 2026, in the journal Nature. This extensive dataset significantly broadens the catalogue of human genetic variation and establishes a population-specific genomic reference for Pakistan. The PGR project involved individuals with high familial relatedness, aiming to capture a more comprehensive understanding of genetic diversity within the Pakistani population. The publication represents a major step forward in genomic research for South Asia, providing a valuable resource for future studies on genetic diseases, population history, and personalized medicine. Researchers anticipate that the PGR will facilitate discoveries related to genetic predispositions and drug responses specific to this demographic. The initiative underscores the growing importance of large-scale biobanks in advancing global health and genetic understanding.