Publisher Correction: White matter micro- and macrostructure brain charts for the human lifespan

Nature published a correction on June 2, 2026, regarding the "White matter micro- and macrostructure brain charts for the human lifespan" study, originally published in the same journal (doi:10.1038/s41586-026-10693-3). The correction addresses specific details within the study's methodology and findings related to the development and aging of white matter in the human brain across the entire lifespan. White matter, composed of nerve fibers, is crucial for transmitting signals between different brain regions and plays a vital role in cognitive functions, motor control, and sensory processing. Changes in white matter structure and integrity are associated with various neurological conditions and the natural aging process.

The original study aimed to create comprehensive "brain charts" that map the typical micro- and macrostructural characteristics of white matter from infancy through old age. These charts are intended to serve as a normative reference, allowing researchers and clinicians to identify deviations from typical development or aging patterns. Such deviations can be indicative of developmental disorders, neurodegenerative diseases, or the effects of environmental factors. The creation of these charts involved analyzing large datasets of brain imaging, likely employing techniques such as diffusion tensor imaging (DTI) to assess white matter microstructure and structural MRI for macrostructure.

The publisher's correction, while not detailing the specific nature of the errors, signifies that certain aspects of the data analysis, interpretation, or presentation within the original publication require amendment. This could involve adjustments to the statistical models used, refinements in the definition of specific white matter tracts, or corrections to the graphical representations of the brain charts themselves. Such corrections are a standard part of the scientific publishing process, ensuring the accuracy and reliability of published research. The implications of this correction are significant for the scientific community relying on these brain charts for comparative studies, diagnostic tools, and the development of targeted interventions for brain health across the lifespan.